D-Lin-MC3-DMA (MC3)
DLin-M-C3-DMA
CAS: 1224606-06-7
Molecular Formula: C43H79NO2
D-Lin-MC3-DMA (MC3) - Names and Identifiers
D-Lin-MC3-DMA (MC3) - Physico-chemical Properties
| Molecular Formula | C43H79NO2 |
| Molar Mass | 642.09 |
| Density | 0.886±0.06 g/cm3(Predicted) |
| Boling Point | 670.2±43.0 °C(Predicted) |
| Solubility | DMSO : ≥ 43.33 mg/mL (67.48 mM) ; Ethanol : 16.67 mg/mL (25.96 mM; Need ultrasonic) |
| pKa | 9.37±0.28(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Physical and Chemical Properties | Bioactive D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is an effective and ionizable cationic liposome. D-Lin-MC3-DMA is used to deliver siRNA in vivo. |
| Use | The chemical name of the DLIN-M-C3-DMA is 4-(N,N-dimethylamine) butyric acid -6,9,28, 31-tetraene-19-trimetanol ester, which can be used to prepare liposome preparations. Liposome preparations include complementary double positive lipids, phospholipids and long-acting lipids. Complementary double positive lipids include: the first positive lipid and the second positive lipid. DLIN-M-C3-DMA can be used as the first positive lipid. |
D-Lin-MC3-DMA (MC3) - Upstream Downstream Industry
D-Lin-MC3-DMA (MC3) - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.557 ml | 7.787 ml | 15.574 ml |
| 5 mM | 0.311 ml | 1.557 ml | 3.115 ml |
| 10 mM | 0.156 ml | 0.779 ml | 1.557 ml |
| 5 mM | 0.031 ml | 0.156 ml | 0.311 ml |
Last Update：2024-01-02 23:10:35
D-Lin-MC3-DMA (MC3) - Introduction
DLin-M-C3-DMA, also known as DMBAE, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: DMBAE is a colorless liquid
-Molecular formula: C13H25NO2
-Molecular weight: 227.34g/mol
-Melting point:-30 ° C
-Boiling point: 318-332 ° C
-Density: 0.956 g/mL
Use:
- DMBAE is widely used in coatings and adhesives as a plasticizer.
-It can also be used as a reactive diluent, which can reduce the viscosity of the coating and chemically react with other compounds during the curing process.
Preparation Method:
- DMBAE is generally prepared by an acid-catalyzed alcohol amine reaction. First, dioleyl methanol and 4-(N,N-dimethylamino) butyric acid are mixed in a suitable solvent at a molar ratio of 1:1. Under the action of a catalyst, the reaction is heated, generate DMBAE.
Safety Information:
- DMBAE is a flammable liquid, away from fire and high temperature environment.
-Avoid direct contact with skin and eyes, and take personal protective measures, such as glasses, gloves and protective clothing, if necessary.
-Pay attention to ventilation during operation and avoid contact with strong oxidants.
-If inhalation or skin contact occurs, immediately stay away from the source, wash the affected area, and seek medical help.
-please read the product safety data sheet (SDS) before use.
Nature:
-Appearance: DMBAE is a colorless liquid
-Molecular formula: C13H25NO2
-Molecular weight: 227.34g/mol
-Melting point:-30 ° C
-Boiling point: 318-332 ° C
-Density: 0.956 g/mL
Use:
- DMBAE is widely used in coatings and adhesives as a plasticizer.
-It can also be used as a reactive diluent, which can reduce the viscosity of the coating and chemically react with other compounds during the curing process.
Preparation Method:
- DMBAE is generally prepared by an acid-catalyzed alcohol amine reaction. First, dioleyl methanol and 4-(N,N-dimethylamino) butyric acid are mixed in a suitable solvent at a molar ratio of 1:1. Under the action of a catalyst, the reaction is heated, generate DMBAE.
Safety Information:
- DMBAE is a flammable liquid, away from fire and high temperature environment.
-Avoid direct contact with skin and eyes, and take personal protective measures, such as glasses, gloves and protective clothing, if necessary.
-Pay attention to ventilation during operation and avoid contact with strong oxidants.
-If inhalation or skin contact occurs, immediately stay away from the source, wash the affected area, and seek medical help.
-please read the product safety data sheet (SDS) before use.
Last Update：2024-04-10 22:29:15
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Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Multiple SpecificationsSpot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
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Product Name: D-Lin-MC3-DMA Visit Supplier Webpage Request for quotationCAS: 1224606-06-7
Tel: +86-18821248368
Email: Int06@meryer.com
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View History
D-Lin-MC3-DMA (MC3)
7,7-二甲基-6,7-二氢-1H-吡唑并[4,3-c]吡啶-5(4H)-羧酸叔丁酯
3-甲氧基-4-乙氧基苯甲醇
5-甲基-2-(苯基乙炔)吡啶
(R)-2-苯基-CBS-恶唑硼烷甲苯溶液
2,4-二氯-7-甲基-7H-吡咯并[2,3-D]嘧啶
(S)-2 - ((1R,2S)-3-(苄氧基)-1-羟基-2-甲基-3-氧代丙基)吡咯烷-1-甲酸
4-甲氧基-3-硝基苯乙铜
ALMITRINE DIMESILATE
反式-2-(3,5-二甲氧基苯基)环丙烷-1-羧酸
7,7-二甲基-6,7-二氢-1H-吡唑并[4,3-c]吡啶-5(4H)-羧酸叔丁酯
3-甲氧基-4-乙氧基苯甲醇
5-甲基-2-(苯基乙炔)吡啶
(R)-2-苯基-CBS-恶唑硼烷甲苯溶液
2,4-二氯-7-甲基-7H-吡咯并[2,3-D]嘧啶
(S)-2 - ((1R,2S)-3-(苄氧基)-1-羟基-2-甲基-3-氧代丙基)吡咯烷-1-甲酸
4-甲氧基-3-硝基苯乙铜
ALMITRINE DIMESILATE
反式-2-(3,5-二甲氧基苯基)环丙烷-1-羧酸
Raw Materials for D-Lin-MC3-DMA (MC3)
6,9,28,31-Heptatriacontatetraen-19-ol, (6Z,9Z,28Z,31Z)-
4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
CIS,CIS-9,12-OCTADECADIENOL
9,12-Octadecadien-1-ol, methanesulfonate, (9Z,12Z)-
4-(Dimethylamino)butanoic acid
4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
CIS,CIS-9,12-OCTADECADIENOL
9,12-Octadecadien-1-ol, methanesulfonate, (9Z,12Z)-
4-(Dimethylamino)butanoic acid